Effects of methods and basis sets on calculation results using various solvation models
DOI: https://doi.org/10.15407/hftp09.01.003
Abstract
Various quantum chemical approaches including ab initio, density functional theory (B3LYP, CAM-B3LYP, ωB97X-D, M06HF) and semiempirical (PM7) methods with different basis sets and various solvation models (SMD, IEFPCM, COSMO), as well as a supermolecular approach, and the basis set superposition error (BSSE) corrections, used to analyze the solvation effects are compared for polar (water, ethanol, dimethylsulfoxide, acetonitrile, acetone), weakly polar (chloroform) and nonpolar (benzene, n-hexane, carbon tetrachloride) solvents per se and interacting with unmodified and modified silicas. The DFT methods give smaller errors in the DGs values than the PM7 method with various solvation models. For the molecular clusters with water alone or water with organics, the interaction energy decreases with enhanced amorphism of the systems. The supermolecular approach with PM7 gives worse results (in comparison to the experimental data) than those of SMD/PM7 or COSMO/PM7. An increase in the basis sets can give worse results than that at smaller ones because the parameters in the SMD model were calibrated using the experimental data and ab initio or DFT calculations of the same systems with relatively small basis sets.
Keywords
References
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DOI: https://doi.org/10.15407/hftp09.01.003
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